Settings in tabs "Chan 1", "... 2", "... 3" and "... 4" are meant to be network/channel dependent. Before clicking on the "Apply" button remember to check the combobox containg the network/channel' s name. Your settings in all those four tabs will be saved for that network/channel and only.
The "Self" tab though, is network-independent. This means that your settings there, will apply to all networks.
• Note: Although tab' s "... 4" option to protect users in protect list is network/channel dependent as described above, the users in that list are the same for all networks/channels. You cannot save different users for different networks/channels.